Genetic engineering of mesenchymal stem cells by non-viral gene delivery
نویسندگان
چکیده
منابع مشابه
Gene Delivery to Mesenchymal Stem Cells
There is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. These studies encompass different applications from targeted homing of Mesenchymal Stromal (stem) Cells (MSC), to arming them with different cytokines. Resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...
متن کاملgene delivery to mesenchymal stem cells
there is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. these studies encompass different applications from targeted homing of mesenchymal stromal (stem) cells (msc), to arming them with different cytokines. resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...
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The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
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Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...
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ژورنال
عنوان ژورنال: Clinical Hemorheology and Microcirculation
سال: 2014
ISSN: 1386-0291
DOI: 10.3233/ch-141883